A winner at the Cheltenham Festival in 2016, the Rich Ricci-owned seven-year-old was twice placed at the Galway Festival on the Flat in the summer and hit the target in a valuable handicap on Irish Champions Weekend.
Her trainer Willie Mullins is responsible for seven possibles following Tuesday’s scratching stage, including beaten Ebor favourite Stratum.
Aidan O’Brien’s Cypress Creek, winner of the Group Three Loughbrown Stakes at Naas on Sunday, is also among 12 Irish-trained contenders.
The champion jockey took the marathon contest last year with Withhold, and on Sweet Selection in 2016.
The Brazilian will team up with Vis A Vis after his services were acquired by trainer Neil Mulholland.
The Bath handler bought the son of Dansili out of French trainer David Smaga’s stable for £31,500 and the four-year-old has already proved to be a good purchase by winning both his starts.
Mulholland has saved Vis A Vis for Newmarket since he defeated fellow Cesarewitch contender Just In Time at Kempton in August.
“The Cesarewitch has been the plan with Vis A Vis ever since he won at Kempton, we wanted to make sure we kept his weight low,” he said.
“Initially we weren’t too sure if he would squeeze in near the bottom of the weights, so it’s good that he’s now assured of a place in the field.
“Everything is fine with him and he looks well. He did a nice piece of work the other day and I am very happy with him – as far as I know, Silvestre de Sousa will ride him in the Cesarewitch.
“It’s a great race with great prize money which produces a fantastic spectacle and it’s just nice to have a horse eligible who looks like he has a real chance.
“Vis A Vis is a very laid-back horse with a good temperament so he should cope with the big field. He’s also won on all types of ground, although we’d like to see some moisture in the surface come the big day.”
Ian Williams is the British trainer with the most entries – four – including Stars Over The Sea, facile winner of the Cesarewitch Trial, while John Gosden, successful in the Cambridgeshire thanks to Wissahickon, could complete the Autumn Double with either Precious Ramotswe or Almoghared.
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