The Aidan O’Brien-trained colt failed to add to his Epsom victory last term, but he did notch up three more Group One places, including when third in the Breeders’ Cup Turf.
He is one of three possible Ballydoyle challengers along with Derby fourth and fifth, Broome and Sir Dragonet, who was second on his return in March before racing was suspended.
Defoe won the race last year for Roger Varian when it was run at its usual Epsom home and he could try to defend his title, while Ghaiyyath could represent Godolphin and Charlie Appleby.
Relive Anthony Van Dyck's victory in the 2019 Investec Derby
Top stayer Stradivarius is in the mix for John Gosden and Frankie Dettori and he could drop back to 12 furlongs in a prep run ahead of his bid for a Gold Cup hat trick at Royal Ascot next month.
Martyn Meade is also aiming at the Gold Cup with Technician and he took could tackle a shorter distance as a warm up.
Andrew Balding’s Alounak, the Mark Johnston-trained Communique, Desert Encounter from David Simcock’s yard and Richard Hannon’s Floating Artist complete the list of possibles.
Max Vega could try to forward his Classic claims in Friday’s Betsafe Derby Trial at Lingfield.
Ralph Beckett’s charge won the Group Three Zetland Stakes over 10 furlongs on his final start last year and he is a general 25-1 shot for the Derby, which is scheduled to be run on July 4 at Epsom.
Al Aasy is available at odds of 20-1 for the Epsom feature and he is also in contention for the Listed trial after finishing third on his only outing last year.
His trainer William Haggas also has Convict in the mix while Pontefract Listed winner King Carney could feature for Charlie Fellowes.
Zetland third Berkshire Rocco could represent Andrew Balding, with Celestran a contender from the John Gosden stable among an entry of 15.
The Gosden-trained Miss Yoda was second in the Zetland and she could line up in the Betsafe Top Price All Runners Oaks Trial – a race the yard landed last year with subsequent Epsom victor Anapurna.
Gosden also has Chelmsford maiden winner Lake Lucerne in the race while Beckett has Trefoil, winner of her only start last year, and Heart Reef in contention.
The 14-strong entry also features Roger Varian’s Cabaletta, Sweet Solera winner West End Girl and So I Told You, winner of one of her two outings last year.
Select any odd to add a bet